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DOSAGE and ADMINISTRATION
- BUPHENYL® is available in powder form for infants and young children and in tablets for children weighing >20 kg and adults.
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BUPHENYL® is an oral medication and should be taken by mouth, or by nasogastric or gastrostomy tube.
- The usual daily dose of BUPHENYL Tablets and Powder is:
- 450 – 600 mg/kg/day for patients <20 kg
- 9.9 – 13.0 g/m2/day in patients >20 kg
- BUPHENYL® should be taken in equally divided doses with each meal or feeding, three to six times per day.
- The safety or efficacy of doses in excess of 20 grams (40 tablets) per day has not been established.
- BUPHENYL® must be combined with dietary protein restriction and, in some cases, essential amino acid supplementation.
Click here for important safety information
Click here for Full Prescribing Information
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